Natural products genomics

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منابع مشابه

Natural products genomics

Secondary metabolites (or natural products) are often synthesized by multi-modular, multi-domain proteins called non-ribosomal peptide synthetases (NRPS) and polyketide synthases (PKS). Various well-known metabolites produced by microorganisms are listed in Table 1, and examples of structures are shown in Fig. 1. In particular, Streptomyces species are known for their ability to produce a wide ...

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Antimalarial natural products: a review

Objective: Malaria is an infectious disease commonplace in tropical countries. For many years, major antimalarial drugs consisted of natural products, but since 1930s these drugs have been largely replaced with a series of synthetic drugs. This article tries to briefly indicate that some plants which previously were used to treat malaria, as a result of deficiencies of synthetic drugs, have rev...

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New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18

Marine actinobacteria are drawing more and more attention as a promising source of new natural products. Here we report isolation, genome sequencing and metabolic profiling of new strain Streptomyces sp. MP131-18 isolated from marine sediment sample collected in the Trondheim Fjord, Norway. The 16S rRNA and multilocus phylogenetic analysis showed that MP131-18 belongs to the genus Streptomyces....

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ژورنال

عنوان ژورنال: Microbial Biotechnology

سال: 2008

ISSN: 1751-7915

DOI: 10.1111/j.1751-7915.2008.00044.x